Hsjughl Uk Vwd

You may also find the information useful if you are concerned that you might have a bleeding disorder.

Hsjughl uk vwd. Type 1 vwd accounts for 60 80 of all vwd cases and is a quantitative heterozygous defect of the vwd gene resulting in decreased production. It arises from a deficiency in the quality or quantity of von willebrand factor vwf a multimeric protein that is required for platelet adhesion as well as humans it is known to affect several breeds of dogs. It gives a general introduction to vwd and information on diagnosing treating and living with the condition. People with vwd have a low level of a substance called von willebrand factor in their blood or it does not work very well.

تسعي وزارة الداخلية في المملكة العربية السعودية لتسهيل جميع الخدمات التي تتيحها للمواطنين وتم تقديم العديد من الخدمات المتوفره إلكترونيا لكي يساهموا في توفير المزيد من الوقت والجهد للمواطنين وهم يوفرونه لأصحاب. Vwf is the product of the vwf gene vwf on the short arm of chromosome 12 and. Vwd first described by erik von willebrand in a scandinavian family 1 is characterized by abnormal quantity or quality of von willebrand factor vwf a large glycoprotein synthesized by megakaryocytes and endothelial cells and released into the circulation through a constitutive pathway and also upon stimulation. There are four hereditary types of vwd which are classified as type 1 type 2 type 3 and pseudo or platelet type.

It has two main functions. Von willebrand disease vwd is a common inherited condition that can make you bleed more easily than normal. This booklet is for anyone who has been diagnosed with a bleeding disorder called von willebrand disease vwd. Acquired types of vwd have also been described and usually have autoimmune involvement.

Vwf is a multimeric glycoprotein encoded for by gene map locus 12p13 31. Von willebrand s disease vwd results from the deficiency or abnormal function of von willebrand factor vwf. Von willebrand disease vwd is the most common hereditary blood clotting disorder in humans.